How Long Does It Take for Ambien to Kick in? Ambien (zolpidem) is a fast-acting sedative typically prescribed for short-term treatment of insomnia. It usually starts to work within 15 to 30 minutes after taking it. Because of its rapid onset, it’s important to take Ambien right before you plan to go to bed and only when you can stay in bed for a full night (7–8 hours). Taking it too early or remaining active after taking it may lead to memory issues or sleepwalking. Avoid heavy meals before taking Ambien, as food can delay its absorption and effectiveness. Always follow your doctor’s instructions for safe use.
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